For a patient in her second trimester of pregnancy with a yeast infection, which treatment is usually prescribed for nonpregnant patients but is a Pregnancy category C?

The treatment that is typically prescribed for yeast infections in nonpregnant patients but is classified as a Pregnancy Category C drug is Diflucan (fluconazole) 150 mg. This classification indicates that animal reproduction studies have shown an adverse effect on the fetus, and there are no adequate and well-controlled studies in humans. Therefore, while it may be used in some cases of complicated or severe fungal infections in pregnant patients, its use is approached with caution.

In clinical practice, monotherapy with a topical antifungal like Monistat (miconazole) or Terazol 3 (terconazole) is preferred in pregnant patients because these medications have established safety profiles and are indicated for use during pregnancy. Cleocin vaginal cream (clindamycin) is used for bacterial infections rather than yeast infections and also has special considerations regarding its use in pregnancy. Thus, while they might be effective in treating yeast infections, Diflucan is not the first-line recommendation during pregnancy due to its classification, making it essential to balance the treatment's efficacy with potential risks to the developing fetus.